Let’s talk about cortisol—aka your stress hormone MVP. It’s the one your body releases to help you “fight or flee” when things get intense (like a work deadline, a HIIT workout, or, you know… traffic). This is a form of acute stress, a short-term response to various stressors that can trigger cortisol release. Effective stress management is crucial here because it helps in managing cortisol levels. But what happens when cortisol doesn’t shut off? Spoiler alert: chaos.

What Is Cortisol?

Cortisol is made in your adrenal glands and plays a huge role in energy, blood sugar regulation, sleep-wake cycles, inflammation, immune system response, and—yep—stress. When faced with stress, the body reacts by releasing cortisol, which helps in immediate reactions but can cause issues if prolonged. A healthy cortisol rhythm looks like this: it spikes in the morning (hello, energy!) and gradually drops throughout the day to help you wind down for bed.

But if you’re constantly stressed or your body’s out of sync, cortisol can either stay too high or dip too low—both of which can cause serious health issues.

Symptoms of a Cortisol Imbalance

Here’s what can happen when cortisol is out of balance:

  • High cortisol symptoms:
  • Trouble sleeping (especially waking between 2–4 AM)
  • Anxiety, racing mind
  • Belly fat that won’t budge
  • Blood sugar crashes or hanger
  • Hormonal imbalances (yes, it messes with estrogen, testosterone, thyroid)
  • Fatigue that hits mid-afternoon but you’re wired at night
  • Brain fog or memory issues
  • Low cortisol symptoms:
  • Exhaustion that doesn’t improve with rest
  • Low blood pressure or dizziness when standing
  • Cravings for salt or sugar
  • Frequent illness or slow healing
  • Depression or flat mood

And yes—you can have high and low cortisol throughout the same day. That’s why it can be so hard to detect without proper testing. Recognizing cortisol imbalance is crucial as it can significantly impact your mental health, contributing to conditions like depression and anxiety. People can feel overwhelmed by these symptoms and should seek help from healthcare providers if needed.

What Causes Cortisol Dysregulation and Chronic Stress?

Cortisol gets knocked off balance for lots of reasons, including chronic disease:

  • Chronic stress 
  • Overtraining or lack of recovery
  • Poor sleep or shift work
  • Blood sugar instability
  • Inflammation or gut issues
  • Underlying infections 
  • Nutrient deficiencies (especially B vitamins, magnesium, and vitamin C)
  • Life changes, such as starting a new job

Why Cortisol Imbalance Often Goes Undetected

Here’s the kicker: cortisol won’t always show up as “high” or “low” on a random blood test. That’s because cortisol follows a diurnal rhythm, meaning it changes throughout the day. If you’re only testing it once in the morning with bloodwork, you’re likely missing the full picture. Preliminary research into cortisol rhythms suggests that understanding these patterns is crucial for accurate diagnosis and treatment. Additionally, understanding different aspects of health, including physical and emotional well-being, is crucial for accurate diagnosis and treatment.

How to Test for Cortisol Properly

The best way to diagnose cortisol issues is through a 4-point salivary or dried urine test, like the DUTCH Complete. This test shows your cortisol curve throughout the day—morning, mid-day, evening, and bedtime—so we can see how your adrenals are actually functioning in real time, backed by scientific evidence.

At Yoo Direct Health, we use diurnal cortisol testing as part of our functional medicine approach when patients report energy crashes, hormonal chaos, or unexplained fatigue.

Functional Medicine: A New Perspective on Cortisol Management

Functional medicine is revolutionizing how we approach healthcare, especially when it comes to managing chronic stress and cortisol levels. Unlike conventional medical care, which often focuses on treating symptoms, functional medicine aims to uncover and address the root causes of health issues. This holistic approach considers the whole person—physical, emotional, and environmental factors—to develop a personalized plan for managing cortisol.

Functional medicine practitioners use a blend of conventional medical care and integrative health approaches to help patients manage stress and balance their cortisol levels. By addressing the underlying causes of chronic stress, such as poor nutrition, lack of sleep, and emotional stressors, functional medicine can help reduce the risk of developing chronic diseases like heart disease, diabetes, and irritable bowel syndrome.

Dietary supplements, stress management techniques, and lifestyle changes are often recommended to help patients manage their cortisol levels and improve their overall well-being. The goal is to promote whole person health and wellness by addressing the complex interplay between physical, emotional, and environmental factors.

This patient-centered approach empowers individuals to take control of their health and make informed decisions about their care. Functional medicine practitioners stay up-to-date with the latest medical literature and research to provide evidence-based care. The National Center for Complementary and Integrative Health offers resources and information on functional medicine and its applications in managing cortisol levels.

By incorporating functional medicine into their treatment plan, patients can better manage their cortisol levels and reduce their risk of developing chronic diseases. This approach not only helps in managing stress but also promotes overall health and well-being.

Our Nurse Practitioner, Nikki Keserich going over a patient report with her Procedure Nurse, Chelsea Misch.

Mind-Body Therapies for Stress and Cortisol Balance

Mind-body therapies like meditation, yoga, and guided imagery are powerful tools for reducing stress and balancing cortisol levels. These therapies work by promoting relaxation, reducing muscle tension, and improving mood, making them an excellent complement to conventional medical care.

Research has shown that mind-body therapies can effectively reduce symptoms of anxiety and depression, improve sleep quality, and enhance overall well-being. They can be adapted to suit individual needs and preferences, making them accessible and convenient options for managing stress and cortisol levels.

For those experiencing high levels of stress and anxiety, the Crisis Lifeline provides free and confidential support, connecting callers with local resources and services. Additionally, the National Institutes of Health offers information and resources on mind-body therapies, including their safety and effectiveness.

Mind-body therapies can also be used to manage chronic pain, improve immune function, and enhance overall health and wellness. Preliminary research suggests that these therapies may positively impact cortisol levels and the body’s stress response.

Whether practiced at home, in a group setting, or with the guidance of a qualified practitioner, mind-body therapies offer a flexible and convenient way to manage stress and cortisol levels. By incorporating these practices into your daily routine, you can support your body’s ability to handle stress and maintain optimal health.

Natural Ways to Balance Cortisol and Reduce Stress

Before we dive into supplements, here are a few lifestyle tools that support healthy cortisol levels:

  • Prioritize sleep: Aim for 7–9 hours and reduce blue light at night.
  • Eat balanced meals: Don’t skip meals—especially protein at breakfast.
  • Manage stress: Breathwork, therapy, journaling, boundaries—whatever helps. Muscle relaxation techniques can also be highly beneficial for reducing stress.
  • Guided imagery: This technique promotes relaxation and rejuvenation, helping to manage stress effectively.
  • Don’t overdo it with workouts: More isn’t always better. Recovery is key.
  • Sunlight in the morning: This helps set your cortisol rhythm naturally.
  • Breathing exercises: These are key relaxation techniques that can help manage a range of conditions.

Nutrition and Cortisol

Nutrition plays a critical role in managing cortisol levels and promoting overall health and well-being. A healthy diet that includes plenty of fruits, vegetables, and whole grains can help reduce cortisol levels and promote relaxation. Certain nutrients, such as vitamin C and omega-3 fatty acids, have been shown to have a positive impact on cortisol levels and overall health.

Chronic stress can lead to changes in eating habits and metabolism, making it more challenging to manage weight and promote overall health. A registered dietitian or healthcare provider can help individuals develop a personalized nutrition plan to manage cortisol levels and promote overall health. Nutrition counseling can be an effective way to address underlying nutritional deficiencies and promote overall health and well-being.

The gut-brain axis plays a critical role in regulating cortisol levels and overall health, and nutrition can have a positive impact on this axis. Certain foods, such as those high in sugar and saturated fat, can exacerbate cortisol levels and promote inflammation. A balanced diet that includes plenty of whole foods and minimizes processed and packaged foods can help promote overall health and well-being.

Nutrition is an essential component of integrative health approaches and can be used in conjunction with other therapies, such as massage and mind-body therapies, to promote overall health and well-being. By focusing on a nutrient-rich diet, you can support your body’s ability to manage stress and maintain optimal health.

Our Favorite Cortisol-Supporting Supplements

We love supporting the adrenal system with the right nutrients and adaptogens. Here’s what we offer at Yoo Direct Health:

  • Adrenotone: helps balance cortisol by supporting the adrenal glands with B vitamins, vitamin C, and adaptogenic herbs like rhodiola and ashwagandha. It boosts resilience to stress and helps regulate both high and low cortisol levels throughout the day.
  • Catchecola Calm: helps lower elevated evening cortisol with phosphatidylserine and calming herbs, making it easier to wind down and fall asleep. It’s especially helpful for people who feel mentally alert or anxious at night when cortisol should be dropping.
  • Tides D-Stress: supports healthy cortisol rhythms by targeting the nervous system—especially for those who feel wired at night and tired in the morning. It boosts GABA and melatonin pathways to calm the brain, promote restful sleep, and help reset flipped cortisol patterns.
  • Vitamin C: helps regulate cortisol by supporting adrenal function and buffering your stress response. It also reduces inflammation caused by high cortisol and supports better sleep and recovery.

P.S. We always personalize supplement recommendations based on your labs and symptoms. There’s no one-size-fits-all in functional medicine. Integrative approaches can also help manage conditions like fibromyalgia by combining various therapeutic modalities to address diverse needs.

The Bottom Line

If you feel like your stress response is stuck in overdrive, your sleep is off, your energy is unpredictable, and your hormones are all over the place—it might be time to look at cortisol.

With the right testing, support, and personalized treatment plan, we can help bring your adrenals (and your entire system) back into balance. If you’re curious about your cortisol levels, book a visit with our team—we’ll get you tested, supported, and back to feeling like yourself again. It’s important to consult health care providers for managing cortisol levels and overall well-being.

Learn more on The Better Yoo Podcast!